The rabbit monoclonal antibody L16-G2 specifically binds to the scFv region of a CD20-specific mouse monoclonal antibody (mAb, clone Leu16). CD20(cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of Leu16 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.
| Product No. | 214202 |
| Size | 100 tests |
| Recommended Vol. per Test | 1 µL |
| Antibody Types | Monoclonal |
| Antibody Format | Whole IgG |
| Clone | L16-G2 |
| Immunogen | scFv region of a CD20-specific Mouse mAb clone Leu16 |
| Conjugate | Alexa Fluor 647 |
| Excitation/Emission Max | 651/667nm |
| Host Species | Rabbit |
| Reactivity | Mouse |
| Storage Buffer | Aqueous buffered solution containing protein stabilizer and ≤0.05% ProClin 300 |
| Storage conditions | 2-8°C, store in dark |
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