PureBind F(ab’)2 Fragment Anti-Leu16 scFv Monoclonal Antibody (Clone L16-1G12), Alexa Fluor 647 (25 tests)

Description

The rabbit monoclonal antibody L16-1G12 specifically binds to the scFv region of a CD20-specific mouse monoclonal antibody (mAb, clone Leu16). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of Leu16 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Product Infomation

Preparation & Storage

• Store undiluted at 2-8°C.
• Avoid prolonged exposure to light.
• Avoid freeze/thaw cycle of the reagent.
• The monoclonal antibody was purified by Protein A.
• The antibody was conjugated with Alexa Fluor 647 under optimum conditions, and unincorporated dye was removed.