Rabbit Anti-Mouse 14G2a scFv, Monoclonal Antibody (Clone 14B06), Alexa Fluor 647 (25 tests)

Description

The rabbit monoclonal antibody 14B06 specifically binds to the scFv region of a GD2-specific mouse monoclonal antibody (mAb, clone 14G2a). Disialoganglioside GD2 is a glycosphingolipid highly expressed on neuroblastoma, melanoma, and other tumors of neuroectodermal origin, with limited expression in normal tissues. The scFv region of 14G2a has been used to develop GD2-specific chimeric antigen receptor (CAR) T cells utilized in preclinical studies and clinical trials.

Product Infomation

Preparation & Storage

• Store undiluted at 2-8°C.
• Avoid prolonged exposure to light.
• Avoid freeze/thaw cycle of the reagent.
• The monoclonal antibody was purified by Protein A.
• The antibody was conjugated with Alexa Fluor 647 under optimum conditions, and unincorporated dye was removed.