Precision CAR-Monitoring
High-Sensitive Anti-ID Ab for PK/PD and ADA Assessment
- CytoArt is the first commercial producer of anti-idiotype antibody for CAR-T detection. We cover 6 FDA-approved CAR-T targets worldwide.
- Our product portfolio enables robust CAR molecule tracking (PK/PD) and highly sensitive detection of anti-drug antibodies (ADA) across diverse technology platforms, including Flow Cytometry, ELISA and MSD.
- Data Integrity – Provide reproducible, regulatory-grade evidence to support clinical decision-making.
In vivo CAR Engineering
Empowering the Next Generation of Cell Therapy with VHH Nanobody Solutions
- VHHs (Nanobodies) are compact, ultra-stable antigen-binding domains that offer superior tissue penetration and modularity for complex therapeutic designs.VHHs can serve as both high-affinity CAR constructs and precision targeting heads to reprogram T cells in invivo CAR engineering.
- We leverage cell-based screening to ensure VHHs recognize target proteins in their native conformation with pM-level binding potency. Our antibodies are rigorously validated for high specificity with negligible non-specific binding, ensuring a superior safety profile for clinical translation.
Our Technology Platform Excellence
Specialized Antibody Solutions with Guaranteed Quality
CytoArt boasts years of technical expertise with extensive experience in antibody discovery and production. Powered by a proprietary platform, a specialized team, and over 8 years of focus on anti-idiotypic antibodies, we enable rapid generation of high-quality antibodies (including VHHs)—delivering monoclonal antibodies in as few as 20 weeks.
Solutions for NHP Models
Rapid Assay Optimization & Technical Troubleshooting
Leu16-scFv anti-CD20 CAR, effective in both human and non-human primate (NHP) models, has become a widely adopted model for evaluating in vivo CAR-T delivery and function in preclinical animal studies.
To address the challenge of non-specific binding in monkey blood, we have optimized our antibody to significantly reduce background noise and ensure reliable assay results.
Global Partners
